Protein Design Boosts Immune Response to Cancer – Al Manar Canal – Lebanon



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US researchers have been able to redefine a protein that has been shown to be effective in boosting the ability of immune cells to fight kidney and skin cancers.
In the study published in the journal Nature, the researchers announced that they have been able to redefine the "interleukin-2" protein that is effective against cancer, while avoiding serious effects.
"For patients with kidney cancer or skin cancer, this protein can save lives, but its dose that fights cancer can produce side effects," said Daniel Adriano Silva Manzano, biochemist at the University of Washington (UW), lead author of the study. Threatening life. "
"We have managed to use computer models to design a new protein from scratch, which simulates its capabilities while avoiding its serious side effects."
The researchers decided to name the modified version "Neo-2/15", which concerned only 14% of the amino acid sequence of the original protein.
According to the results published in the journal, the modified protein has altered the growth of the tumor during animal testing and will soon be tested on humans.

Source: New

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