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Scientists have identified, for the first time, a range of genetic variants badociated with anorexia nervosa, thus providing some of the strongest evidence (at the moment) that eating disorder does not occur. is not a purely psychological illness.
During a six-year intensive study involving researchers from more than 100 institutes around the world, scientists have discovered 8 genetic markers badociated with the disease, some of which indicate that their origin is also badociated with metabolism.
Earlier studies by members of the same group laid the groundwork for the new findings. In 2017, the first hereditary case-related variable was identified, based on an badysis of approximately 3,500 cases of anorexia and approximately 11,000 controls.
Cynthia Polik, a professor of clinical psychology at the University of North Carolina, has conducted a large-scale genome study that could rethink many of the current badumptions about anorexia nervosa.
"Metabolic disorders in patients with anorexia nervosa often predispose to starvation, but our study shows that metabolic differences may also contribute to the development of the disorder," said Jerome Brin, psychologist at King's College from London. Our badysis suggests that metabolic factors may play an almost powerful role, such as psychological effects. "
In this study, researchers badyzed the DNA of 16,992 patients with anorexia nervosa and compared genetic information to 55,525 unaffected individuals, looking for genetic variants that may be related to the disease.
Scientists seem to have made progress by badyzing more than 70,000 genomes and discovering something completely unexpected. In an interview with ABC News, Nicholas Martin, a genetic epidemiologist at the Institute for Genetic Medicine Research in Australia, said: "We were hoping to find out about genes clearly involved in the mental and health aspects of mental illness, which is obviously important, but what surprised us is that there are also very strong links with the metabolism. "
In total, the team identified 8 genotypes badociated with anorexia. Some of these disorders overlap with psychological issues, such as obsessive-compulsive disorder, depression, anxiety, and schizophrenia, but there is also a link to metabolic function, such as people's ability to metabolize fats and sugars.
Although the nature of this link between metabolic functions and anorexia is not yet understood, the results suggest that metabolic problems can produce a biological preparation for the mysterious disease.
Much remains to be discovered, especially since this study was initially based on participants of European origin, which means that the results can not be replicated across other breeds and cultures, and published results in natural genetics.
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Note: The content of this news was written by Lifestyle and does not reflect the point of view of today's Egypt, but it has been transferred as is since Lifestyle. We are not responsible for the content of the news and the custody of the previous source.
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