Study: Excessive obesity weakens renal function

A large study suggests that kidney function is likely to deteriorate with an increase in obesity, whether or not he suffers from kidney problems.

The study found that obese adults were twice as likely to have kidney failure than just overweight adults.

"Excess weight, especially around the abdomen, causes many negative metabolic effects on the kidneys," said Dr. Alex Chang, lead author of the study.

Zhang said by email that this extra weight can activate the sympathetic nervous system or the sympathetic nervous system, which secrete hormones that can increase sodium retention and blood pressure. This also makes it difficult for the body to get rid of extra sugars in the blood, which leads to diabetes.

All of these things are bad for the kidneys, Zhang added, adding that infections badociated with obesity and excess abdominal fat also weaken kidney function.

"First, weight gain increases the activity of the sympathetic nervous system and hormones that result in increased sodium retention and high blood pressure." Second, excess weight weakens the body's ability to transfer the glucose from the blood to the cells and can lead to diabetes.

According to WHO data, 1.9 billion adults are overweight or obese in the world. About four out of 10 adults suffer from weight gain, while about one in 10 adults suffers from obesity, a condition that can increase the risk of heart disease, diabetes, joint problems and certain cancers. as well as kidney problems.

For this study, researchers examined data collected from 1970 to 2017 regarding over 5.4 million adults from 40 different countries in Asia, Europe, the Middle East, and North America, and also examined more than 84,000 people at risk of cardiovascular disease, more than 19,000 adults have chronic kidney disease.