What is the new treatment for colitis?

Tomorrow – A medical study examined the use of fecal microbiota transplantation in the treatment of ulcerative colitis, which has been shown to reduce the symptoms of the disease in some people and in others to eliminate it.

The study was conducted by doctors from the University of Adelaide (Australia) and aroused great interest. The British laboratory Microbiotica collaborates with researchers to develop a real treatment based on the microbial technique used in this study .

Dr. Costello, director of the study, said the ultimate goal was to create microbial treatments that would replace the transplant. This could include bacterial pills that have the same benefits as a stool graft, but will be safer and less complex.

Ulcerative colitis is an inflammatory bowel disease that in some cases leads to chronic inflammation of the digestive system. According to the Centers for Disease Control and Prevention, while inflammatory bowel disease affects the entire digestive system, ulcerative colitis usually affects the large bowel and rectum, according to author Brian Mastroiani in his published report. by Healthline.

The author explained that ulcerative colitis is different in terms of severity and that it includes symptoms of blood defecation and colic, pain and bleeding in the rectum and weight loss, stress and fever.

The exact causes of the disease remain a mystery to the doctors. People with ulcerative colitis are more likely to develop colon cancer.

Stools
During the process of implantation of faecal microbes, samples of healthy donor stool are transferred to a person with ulcerative colitis.

This process is primarily aimed at transferring the beneficial intestinal bacteria from the donor to the healthy person so that they can restore the balance of intestinal bacterial bacteria present in the digestive system.

The recent study involved the implantation of anaerobic fecal microbial samples, that is, prepared in an oxygen-free environment, in 73 adult adults with ulcerative colitis. On the other hand, others were subjected to a procedure of implantation of their faeces by colonoscopy, followed by two enemas over a period of seven days.

The transplant, prepared in an oxygen-free environment, reduced the disease by 32%, compared with only 9% for people treated with placebo. Sample preparation in an oxygen-free environment is likely to be the key to this treatment.

"Exposure to oxygen causes the death of many intestinal bacteria, and we know that with the anaerobic treatment of feces, a lot of beneficial bacteria live," said Dr. Sam Costello , a gastroenterologist at the Queen Elizabeth Hospital in Birmingham and a professor of medicine at the University of Adelaide. We transferred it to the patient.

Dr. Benjamin Klein, a gastroenterologist, said the fecal microorganism process helps restore the balance of human microbes, thereby reducing the risk of ulcerative colitis. This process is a very effective method in the treatment of severe Clostridium bacteria, the leading cause of severe diarrhea and inflammation.

Study phase
Dr. Najwa Al-Nashif, a professor of medicine at the University of California at San Francisco, warned that it was important to note that the benefits of stool graft treatment are still in the phase of ## 147 ## 39; study.

"This recent study suggests that the treatment will be beneficial, at least for a group of people, but we do not know yet how it will be," she said.

Although many studies point out the benefits of this treatment, there are certain things to fear, such as the possibility of infection when receiving this treatment.

Dr. Nash stated that she knew very well that news about this type of research was interesting for people with intestinal infections. She also advised people wishing to discover this type of treatment never to try to transplant any kind of transplant, pointing out that the treatment was still under study and that, if it interested them, they should look for hospitals in the course of controlled clinical trials.