[ad_1]
According to the Department of National Statistics, 32.1% for men and 46.8% for men. women in Lithuania use drugs prescribed by a doctor and 46.7% women and 65.2 percent men – non-prescribed medicines, herbal remedies and vitamins. A third of them do not follow the instructions for using the drugs. This suggests that many do not take into account the risks of medication side effects.
Severe drug hepatitis can catch up even young people. Dr. J. Šumskienė has remembered the story of a young man. He started taking extra exercises with his sports activities and wanting to develop his muscles. It is suspected that they may contain androgen hormones.
"The boy wanted to look like a movie hero, and became a hard patient because he had no liver." Although he did not admit to using hormones, the so-called androgens, but studies have shown that it is these substances that stimulate muscle growth that could damage the liver.The drug hepatitis has developed, which has suffered for several months " said Dr. J. Šumskienė.
Even the desire to get rid of overweight can be fatal to the liver. A doctor went to Dr. J. Sumskiene. She tried to lose weight by buying herbal products from the Chinese market. When a woman was hospitalized, she was diagnosed with inflammation of the liver, but the specialists failed to determine which combination of substances had such effects.
Hepatitis can also develop due to misuse of antiviral drugs. Medications for fever and colds that can be purchased at the pharmacy without a prescription can also be exacerbated if a person self-medicates. High doses of paracetamol are particularly dangerous. Paracetamol is often used as one of the ingredients for treating colds. This is also the case for people who want to quickly recover different names but who manufacture tablets of similar composition and drink them one by one.
There are sad stories about the side effects of drugs. It happened to a girl who drank a lot of paracetamol tablets, not even remembering how much they were. The state of affliction was difficult. The doctors were unable to save her even though the liver was transplanted.
What is a drug hepatitis? Why is it important to talk about it? – I asked the doctor gastroenterologist J. Šumskiene.
The medical literature indicates that drug lesions are not uncommon. There are no precise statistics in Lithuania, but the morbidity and mortality due to these violations are high. More than 1,000 cases of acute drug-induced liver failure are reported each year, including 41%. because of the toxic effects of acetaminophen.
It is not possible to establish a complete list of drugs that cause liver damage. There would be more than a thousand. It must be understood that this only happens under certain conditions. For example, the liver may be directly affected by hepatotoxic drugs, the effects of which can be predicted because their toxicity depends on the dose. But there are also unpredictable drugs for the liver, which are independent of the dose, the duration of treatment and the pharmacological action of the drugs.
How Does the Proportion of Cases of Medical Hepatitis Remain Undiagnosed?
It depends on the mechanism of action of the hepatic agent, the dose, the patient's body condition. The violation can occur with typical signs of other diseases: vomiting, nausea, jaundice, abdominal pain, weakness.
There are no reliable diagnostic methods either. Drug lesions of the liver are suspected if treatment is discontinued, the disease improves, and liver enzymes are improved. When the diagnosis is not clear, other hepatic diseases – hepatitis A, B, C, cytomegalovirus hepatitis, alcoholic liver injury, hepatic collapse – steatosis should be excluded. Because it is difficult to diagnose, about 20-30% cases of drug hepatitis remain unidentified.
What are the types of drug hepatitis?
Drug-induced hepatitis can be broken down by duration, for example, lightning, when the symptoms of liver damage develop over a few days or weeks: brilliant jaundice, bleeding disorders, complications of Hepatic failure that develop develop neurological and psychiatric disorders.
Drug-induced hepatitis may also be acute when the disease develops up to 3 months. Another form of this disease is chronic drug hepatitis that lasts more than three months.
What are the diseases that can crush?
If the liver is damaged by the direct action of hepatotoxic drugs, the clinic may appear very fast and thunderstorm. Hepatic failure progresses progressively. The patient may die if the donor's liver is not transplanted in time. But there are cases where only mild signs of abdominal discomfort are present, then the real cause of the disease is due to changes in lab tests.
What should you do to save a healthy liver?
Before choosing a medicine, it is important to collect as much information as possible, to rationally review your health and to consult your doctor. Hepatic and renal function should be considered in order to evaluate the risk of hepatic insufficiency, and liver enzyme studies should be considered if there is uncertainty about hepatic effects. The effects of liver damage on drugs can be influenced by age, bad, drug use and drug interactions.
It is very important to know if the patient is suffering from chronic liver disease. In patients with various diseases of the liver, the metabolism of the liver is disrupted, the body reacts to the active substance.
It is also important to know if a person is allergic to drugs, not addicted to drugs, alcohol, etc.
How is hepatic imbalance and hepatitis
Nonalcoholic liver disease is one of the most common liver diseases in economically developed countries with risk factors common such as central obesity, type 2 diabetes mellitus, dyslipidemia, metabolic syndrome.
Flush of the liver (steatosis) can also be caused by various medications. Research shows that the incidence of nonalcoholic liver disease in the United States is 30 to 40%, while in the rest of the world this figure ranges from 6 to 35%. It is believed that fatty liver without alcohol is about 3-5%. and high-risk patients (severely obese or diabetic) reach up to 90%.
If a patient uses at least two different types of drugs for a long time, how often is the hepatitis test recommended? Which tests help determine the correct diagnosis?
There are no specific studies specific to medical hepatitis.
For long-term treatment, patients are asked to look for liver enzymes every 6 months, once a year, to perform an ultrasound of the abdominal organs.
Does the public have sufficient information about the side effects of the liver?
An open access database is available for LiverTox as well as the website of the National Agency for the Control of Drugs.
In order to avoid drug-induced liver damage or other adverse reactions, the opportunity to use the drug, access to warnings and precautions must be taken into account. In most cases, the liver damages the antibiotics. For example, an amoxacillin and a clavulanic acid derivative of the augmentin, producing toxic effects on the liver, cause cholestatic lesions. Similar effects of other antibiotics.
Nonsteroidal anti-inflammatory drugs are less likely to cause liver dysfunction, but they are one of the most commonly used drugs in Lithuania. The most popular formulations of this pharmacological subtype are acetylsalicylic acid diclofenac and ibuprofen. Nonsteroidal anti-inflammatory drugs cause up to 10% of inflammation worldwide. liver damage.
In addition, the liver may be excreted by antifungal, anti-tuberculosis, contraceptive, cytostatic, certain herbs. I would like to point out that oral contraceptives, anabolic steroids, can lead to the development of tumor adenomas of the liver or liver cancer.
How can we protect liver cells?
The main principle of treatment, which is known since the time of Hippocrates, is not to hurt the patient. If possible, it is necessary to select a drug with the least effects on the liver. Is it possible to start treatment at lower doses and monitor liver function?
Because there is no single reason for hepatitis, a number of factors need to be taken into account. After all, a lot depends on the human body, even when there is an outbreak of influenza, some people drink a lot of paracetamol, but not everyone develops medical hepatitis.
Prophylactic agents for liver protection may be used. If studies show that liver enzymes have increased, doctors usually recommend hepatoprotective treatments – hepatocellular carriers. It can also act of herbal preparations.
It is known that certain herbal extracts that improve liver function also have a protective effect on the liver. Research shows that a new, effective and safe way to help the liver is to use silimarine (actually a brandy extract), curcumin (gourdworm extract), piperine (an extract black pepper).
To help our body stay healthy and able to do its job, the person must work. The enemies of the liver are alcoholic and fatty foods, processed and difficult to digest. In order to respect your body, a person must regulate his diet, do not drink alcohol, to follow the regimes of work and rest. Drug use must be combined with other measures, so only one person can enjoy a long-term well-being.
[ad_2]
Source link
