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"Immunodeficiencies are very rare diseases," said Dr. of the Children's Hospital Center of Oncohaematology. Elena Rascon – and that's one of the main reasons why they have to transplant the bone marrow. "
Having established the Center of Excellence in Primary Immunodeficiency and Acquired at the Children's Hospital, an effective and timely diagnosis was initiated to identify these patients." The patient, who is now a boy of two years undergoing an immunocompromised transplant last year, was particularly vulnerable to damage to the immune system.
A month ago, a bone marrow transplant patient was at the heart of the hospital. 19659003] "The child lived near a year in a hospital, did not get fat, suffered from shortness of breath, constant diarrhea, rash and attacked the baby. ;infection. The only way to correct this defect was to transplant the bone marrow, giving the child a new immunity. That's what we did when we found the right donor abroad.
However, the problems did not stop there: there was a severe and complicated infection after the transplant, a specific infection due to the bacteria used for the TB vaccine. J. Rascon
Having undergone several cycles of antbioses for a transplant against a host, other infections, after one year the immune system of the child has reestablished, and the Doctors believe that the child will be able to continue home treatment after arriving just to check. we have more serious cases of serious illness than we could have: 1-2 children a year get sick, although overall statistics show that these cases should not be more than 1.5 every three years, "says the doctor of # 39; oncohaematology. J. Rascon
The combined immunodeficiency is a hereditary genetic disease when a child gets sick after receiving a specific bad gene from his father and the other from a mother, although both parents be in good health. The disease occurs after the fourth month of the baby's life, and at that time the child is protected from the mother's immunity.
In a mild form of immunodeficiency, a person can live a full life by continuously receiving immunoglobulin injections. Combined immunodeficiency, chronic granulomatous disease, primary haemophagocytosis, and in other cases where the immune cells themselves, the lymphocytes, do not function properly, without bone marrow transplant can not be a cause of disease
In the United States and in other European countries, a complete neonatal screening has been introduced as a result of combined immunodeficiencies
The reason is simple: the child is infected as early as possible by the immune cells until the child reaches immunodeficiency. There is still no respiratory failure, diets have severe infections, the longer the period after transplantation is easy and the better will be the disease, as well as the costs for the state.
How immunodeficiencies are reported in children, or ten signs of immunodeficiency:
1. Four or more ear infections per year.
2. Two or more serious sinus infections over a year.
3. Two or more months of antibiotic treatment with no significant effect.
4. Two or more inflammations of the lungs in the year.
5. The baby is heavily weighed and has a normal developmental disorder.
6. Repetitive, deep skin and internal organs.
7. Permanent thrush in the mouth or fungal infections of the skin.
8. Need intravenous antibiotics to eliminate the infection.
9. Two or more deep infections, including blood contamination.
10. The family has primary immunodeficiency in the family.
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