The WHO recommends a drug to prevent postpartum hemorrhage



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World Health Organization (WHO) recommended a new drug as first choice to prevent excessive bleeding after childbirth because it has proven to be effective in helping to save the lives of mothers in low- and middle-income countries.

The drug, called thermostable carbetocin is an alternative as safe and effective as oxytocin, currently recommended by the organization, but its handling is easier because it does not require refrigeration and remains effective for at least three years.

Oxytocin is very effective, but it must be stored and transported at a temperature between eight and two degrees Celsius. many countries where, when exposed to heat, it loses its effectiveness, depriving women of their beneficial effects.

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A study conducted by WHO, in collaboration with Ferring Pharmaceuticals has shown that thermostable carbetocin is not refrigerated, retains its effectiveness for at least three years stored at 30 degrees Celsius and 75 percent relative humidity.

"This is a truly encouraging new development that can revolutionize our ability to keep mothers and babies alive," said Dr. Tedros. Adhanom Ghebreyesus, general director of WHO

About 70 thousand women die each year due to postpartum hemorrhage, which increases the risk that their average, babies die in less than a year. 39, a month.

The WHO clinical trial focused on approximately 30,000 women who gave birth vaginally in Argentina, Egypt, India, Kenya, Nigeria, Singapore , South Africa, Thailand, Uganda and the United Kingdom, where a single injection of carbetocin or oxytocin was administered randomly to each of them immediately after l & # 39; childbirth. Both drugs were maintained at the required temperatures to ensure their effectiveness.

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Metin Gülmezoglu, Department Reproductive Health and WHO Research, pointed out that the development of a drug to prevent postpartum hemorrhage effective in hot and humid conditions very good news for millions of women giving birth in places without access to refrigeration.

The WHO said in a statement that once proven the effectiveness of carbetocin, the next step is the examination and regulatory approval by the country [19659002] Experts say this paves the way for thermostable carbetocin to offer all women who deliver vaginally in 90 countries worldwide, especially in those where oxytocin can not have the conditions to cooling required

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