The "microdoses" of aspirin reduce the risk of Alzheimer's

A aspirin regime in doses low may represent a new way for to reduce The pathology of Alzheimer's disease according to new research in a mouse model of the disease.

The study identifies a new role for one of the most used drugs in the world.

Although the exact cause of the progression of the disease of Alzheimer the alteration of the elimination of toxic beta-amyloid, especially the hippocampus is unknown, is a prominent mechanism. Therefore, the activation of the cellular machinery responsible for the elimination of brain waste has become a promising strategy to curb the disease.

Based on studies showing a link between aspirin and risk reduction and prevalence of Alzheimer's disease Kalipada Pahan and colleagues at Rush University Medical Center, Chicago, Illinois, USA, demonstrates that this drug reduces the pathology of amyloid plaque in mice by stimulating lysosomes, the component of animal cells that helps eliminate cell wastes.

The survey, details of which revolt on Monday in an article published in "Neurosci", sum of the established uses of aspirin for the relief of pain and for the treatment of cardiovascular diseases

FM