They develop a genetic treatment to relieve cirrhosis

Scientists Mexicans developed a treatment that uses human genes to regenerate the liver and could relieve cirrhosis, a disease caused by alcohol consumption and . Hepatitis C [19799002] Juan Armendáriz, a researcher at the Health Sciences Campus of the University of Guadalajara (UdeG) explained at a press conference that he was using gene therapy that uses Human genes for injecting drugs against diseases that do not have

As part of the World Day of Hepatitis celebrated on July 28, Armendáriz, leader of the research, explained that he was not able to use drugs to treat drugs. they developed adenoviral vectors (modified viruses that do not generate infections) with a metalloproteinase gene known as MMP8.

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These enzymes or proteins are naturally by the body to break down collagen and participate in healing processes, tissue regeneration and against invasion or the metastasis of tumor cells.

Adenoviral vectors with the MMP8 gene were administered in "The technological development we are doing is using a physiological mechanism that the body uses when it uses proteins that degrade the extracellular matrix. or fibrosis in the liver, which helps it to regenerate itself and finally make it functional, "said Jesús García, of the Institute of Molecular Biology in Medicine and Gene Therapy at UdeG

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It explains that it's like they had a factory of these proteins at the muscle level, thanks to genomic medicine that uses adenoviral vectors that carry DNA from the protein to the muscle, which reproduces it and in turn sends it to the liver to regenerate it.

Cirrhosis is not caused solely by consumption alcohol, since only 25% of those who ingest this substance develop this disease, but also for hepatitis C or liver cancer, experts have explained.

According to the World Health Organization (WHO), it is estimated that there are 71 million people in the world with the hepatitis C virus and a considerable number of these patients will develop cirrhosis or liver cancer.

Every year, 399,000 people die from this disease, mainly cirrhosis and hepatocellular carcinoma.

Armendariz has stated that this treatment has up to now It has been used in animals, but it could also be used in patients with diabetic nephropathy and whose kidney has deteriorated.

In the study, researchers from the UdeG and Technology e Monterrey, which has won several awards. EFEUSA

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