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According to a study published by the journal Neuron, a single alcoholic beverage can affect memory formation for hours and cause long-term cravings.
A team from Brown University in Rhode Island (United States) has determined that a molecular shift could help explain why wine glasses can damage memory for days and why alcoholics can relapse after decades of life. 39; abstinence.
In an analysis conducted with flies that, despite the fact that they only have 10,000 neurons (versus 100 billion in humans), share some basic characteristics, the group led by Professor Karla Kaun has discovered a "key" area of the brain. "To justify this prolonged memory loss.
"All drugs – alcohol, opiates, cocaine or methamphetamine – have undesirable side effects and make you feel nauseated or hangover, so why do we find them so rewarding?" Kaun wondered before starting the study.
To solve this problem, Kaun and researcher Emily Pertuccelli of the University of Southern Illinois used genetic tools to selectively disable key genes while causing flies to find alcohol.
One of the proteins responsible for flies' preference for alcohol is Notch, which is part of a signaling pathway involved in the development of embryos and in the development of the adult brain and its functioning in humans and in all animals.
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