Appendix affects Parkinson's disease



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According to a study published in the journal Science Translational Medicine, the appendix serves as a reservoir for the protein lfa-synuclein, associated with this disease that affects memory. Therefore, appendectomy reduces the risk of suffering from Parkinson's disease.

"Our results indicate that the appendix is ​​an original site for Parkinson's disease and is a way to design new treatment strategies that take advantage of the role of the gastrointestinal tract in the development of the disease." ", said the main author, Viviane Labrie.

"Although it has the reputation of being largely useless, the appendix actually plays an important role in our immune system, in regulating the composition of our intestinal bacteria and now, as our work shows, in Parkinson's disease, "said the scientist.

The risk reduction of Parkinson's disease only became evident when the appendix and alpha-synuclein that it contained were removed early in life, years before the ## 147 ## 39, appearance of the disease, suggesting that the appendix could participate in its appearance. .

The removal of the appendix after the beginning of the pathological process, however, had no effect on its progression.

More common. In the general population, people who had an appendectomy were 19% less likely to develop Parkinson's disease, which was amplified in people living in rural areas, with appendectomies resulting in a 25% reduction in the risk of developing the disease. . .

The study found that the incidence of this disease is often higher in rural populations, a trend that has been associated with increased exposure to pesticides.

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