Estrogen, the cause of increased migraine in men

Men with high levels of estrogen – female sex hormones -, appear more susceptible to migraines than those with lower amounts, reveals a study of the Medical Center of the University of Leiden, the Netherlands.

Migraine is a headache of high intensity that handicaps the patient. It is thought that it is caused by an abnormality in a patient. important chemical used by brain cells, called serotonin. During a migraine attack, changes in serotonin affect the blood vessels of the brain.

In Mexico, nearly 20 million patients suffer from this disease. "The first episode generally occurs in childhood but persists throughout life, the greatest peaks occur between 25 and 45 years and they extend to 65 "said Felipe Arturo Vega, an academic of the Faculty of Medicine of . UNAM

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Estrogen and its influence on migraine

L levels of estrogen in the blood, they influence the frequency and severity of migraine in women ; However, "it is not known if sex hormones also affect migraine in men," said study author, Dr. W.P.J. van Oosterhout

For this reason, Dr. van Oosterhout designed research involving 17 men with an average age of 47, who suffered from migraine at least three times per month during the last two years, who were compared to 22 other men without migraine.

"Our research revealed elevated estrogen levels in migraine men, as well as lower testosterone symptoms." van Oosterhout

Trial and error

For the trial researchers measured the levels of estrogen (estrogen) and testosterone in the blood. They took four blood samples from each participant in one day, every three hours. For migraineurs, the first samples were taken in one day without headaches and then daily until the participant has migraine

The study published in the newspaper Neurology found that men with this disease had higher levels of estradiol between their periods of migraine, which means a lower ratio of testosterone to estrogen, of those who do not report headaches.

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All participants were asked about the symptomatology they experienced before deficiencies in testosterone levels in particular It affects your mood, your energy and your sexual performance. Sixty-one percent of men with migraine reported having these symptoms frequently, compared to 27% of men who did not suffer pain.

Although it was only a small sample, Dr. van Oosterhout commented that more equipment should analyze how these hormonal patterns may affect the onset of headache.

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American Academy of Neurology

General Directorate of Social Communication, UNAM / MEXICO PADECEN MIGRAÑA ALMOST 20 MILLION PEOPLE

SAGE Journals / Chronotypes and circadian timing in migraine.