They find the molecular key to delay multiple sclerosis



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BILBAO, Spain (EFE) .- Researchers from the University of the Basque Country (northern Spain) have found a molecular key to delay the progression of multiple sclerosis, a result published in the scientific journal EMBO Molecular Medicine. The Study Center

Multiple sclerosis is an autoimmune disease that attacks and destroys a structure called "myelin sheath" whose integrity is essential for the proper functioning of the brain and spinal cord.

. Current multiple sclerosis is based on modulating the activity of the immune system, and prevents their cells from accessing the central nervous system, and damaging it. These treatments are effective in the early stages of the disease, but they do not prevent progression and progressive functional deterioration.

In the work that has just been published, a receptor called P2X4 has been identified in microglial cells that increases its anti-inflammatory potential, to reduce damage in multiple sclerosis and, most importantly, improve own body repair answers.

According to Dr. María Domercq, of the Department of Neuroscience of the UPV / EHU, who works in the center of Achucarro de Leioa research, "it is a discovery that opens a new path of pharmacological development for treatment of the progressive phase of multiple sclerosis, and with that we want to open a new door to improving the quality of life of people who suffer from it. "

In this ambitious study, coordinated by researchers from the Basque Country, professionals from the Universe also collaborated from Hamburg in Germany and from the Institute of Functional Genomics in Montpellier, France

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