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A vaccine from the early 1900s could be the key to preventing serious complications of diabetes, researchers at Harvard University and the Massachusetts General Hospital (MGH) in the United States
A little over three years after receiving two TB injections four weeks apart, about 50 people with type 1 diabetes experienced Sugar average decrease blood in the long term and for at least five years.
"The gold standard in the treatment of diabetes is to reduce blood sugar. The reduction of blood glucose changes the quality of life and reduces the risk of complications, "said Dr. Denise Faustman, lead author of the study and director of the laboratory of immunobiology of the MGH [19659001] The people in the study were adults with long-term type 1 diabetes, say, that they had had it for at least 10 years.The vaccine is approved by the Food and Drug Administration (FDA) and is officially known as the Bacillus Calmette-Guerin (BCG) vaccine.It has been used against tuberculosis for about 100 years, said Dr. Faustman.
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Scientists have used a measurement called hemoglobin A1C, which estimates the blood sugar level for two or three months. American Diabetes Association recommends that most people healthy onnes maintain the A1C at 7% or less. There were a total of 282 study participants, 52 had type 1 diabetes and were in the BCG group.
Type 1 diabetes is an autoimmune disease, which means that the immune system mistakenly attacks a healthy part of the body. . In this disease, the immune system attacks insulin-producing beta cells in the pancreas.
Someone with this condition must receive insulin through injections or through a small tube inserted into the skin and connected to an insulin pump. 19659009] Faustman mentioned that the changes seen in two previous studies did not appear to come from any usual route, such as an increase in insulin production or lower insulin resistance. They believe that what is happening is a process called aerobic glycolysis, which causes the cells to consume more sugar. The process seems to close when blood sugar levels drop, preventing these levels from going too low, which can also be a problem.
Faustman pointed out that this could mean that the vaccine would also be helpful for people with type 2 diabetes. However, further studies should be done to verify the effectiveness of the vaccine.
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A vaccine from the early 1900s could be key to preventing serious complications of diabetes, researchers at Harvard University and Massachusetts General Hospital (MGH) in the United States reported. 19659001] More than three years after receiving two TB shots four weeks apart, about 50 people with type 1 diabetes have seen their long-term blood sugar levels drop for at least five years
"The gold standard in the treatment of diabetes is to reduce blood sugar, reducing blood sugar changes the quality of life and reduces the risk of complications," said Dr. Denise Faustman, lead author of the study and director of the laboratory. MGH immunobiology.
The subjects of the study were adults with long-term type 1 diabetes, that is, they were at least 10 years old. The vaccine has received approval from the Food and Drug Administration (FDA) and is officially known as the Bacillus Calmette – Guerin (BCG) vaccine. This has been used against tuberculosis for about 100 years, said Dr. Faustman.
Scientists used a measurement called hemoglobin A1C, which estimates blood sugar levels for two to three months. To prevent complications, the American Diabetes Association recommends that most healthy people maintain A1C at 7% or less. There were a total of 282 study participants, 52 had type 1 diabetes and were in the BCG group.
Type 1 diabetes is an autoimmune disease, which means that the immune system mistakenly attacks a healthy part of the body. . In this disease, the immune system attacks insulin-producing beta cells in the pancreas.
Someone with this condition must receive insulin through injections or through a small tube inserted into the skin and connected to an insulin pump. 19659009] Faustman mentioned that the changes seen in two previous studies did not appear to come from any usual route, such as an increase in insulin production or lower insulin resistance. They believe that what is happening is a process called aerobic glycolysis, which causes the cells to consume more sugar. The process seems to close when blood sugar levels drop, preventing these levels from going too low, which can also be a problem.
Faustman pointed out that this could mean that the vaccine would also be useful for people with type 2 diabetes. However, further studies should be done to verify the effectiveness of the vaccine.
