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MONDAY, July 23, 2018 – Until now, this has only worked in mice, but scientists report a discovery that could pave the way for erasing the signs of aging in humans.
In the new study, researchers focused on the function of mitochondria, the central cells of cells. They produce 90 percent of the chemical energy that cells need to survive, according to the study.
When the study team triggered a mutation that causes mitochondrial dysfunction, mice quickly developed wrinkled skin and fur loss. weeks, the mice showed gray hair, reduced hair density, slow motion and lethargy – changes that are all features of aging. Wrinkled skin was observed four to eight weeks after the introduction of the mutation, and females had more severe wrinkles than males.
But when mitochondrial function was reestablished, the mice regained smooth skin and thick fur "To our knowledge, this observation is unprecedented," said study author Keshav Singh , Professor of Genetics at the University of Alabama in Birmingham.
Often, animal research does not produce healthy mice of the same age
the same results in humans. But the authors of the study believe that this discovery opens the door to further study.
"This mouse model should provide an unprecedented opportunity for the development of preventive and therapeutic therapeutic strategies to increase mitochondrial functions for the treatment of skin associated with aging. Capillary pathology and other human diseases in which mitochondrial dysfunction plays an important role, "said Singh in a university press release.
The study was published July 20 in the journal Cell Death and Disease
More Information The US Bureau of Disease Prevention and Health Promotion describes how to protect your health as you age
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