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Just like a boat that has been in the water for a few years, organisms will be on screws, plates and pacemakers inside the body. This is particularly true for bacteria and fungi found elsewhere in the human body, such as the intestines.
Although implants are completely sterile when they enter the body, Danish research demonstrates
. Implants in people who have an infection, but never on implants in healthy patients.
– We did not expect this to happen in patients without symptoms. According to Thomas Bjarnsholt, a professor at the Costerton Biofilm Center at the University of Copenhagen, we have discovered a whole new niche for bacteria and fungi in humans.
New colony of microorganisms
bones, pacemaker parts and skull plates still to be removed from patients.
In addition, they received implants from recently deceased patients
In total, they had implants of 106 people without signs of infection.
In addition, they had a control group of 39 implants to ensure that the microorganisms appeared inside the body and did not come during surgery or subsequent studies.
The implants were placed in the body for 20 seconds before being packaged. 19659002] Someone had not been taken out of the pack at all and had to be completely sterile. This allowed the researchers to see if the method should be reliable.
The researchers found that
- 70% of common implants had more bacterial and fungal species.
- The plants were not infected with harmful bacteria or
- There were no microorganisms on the control implants
The study does not show how long an implant must be inside the body before it releases fungi and bacteria.
I did not think we would find anything. There will probably be microorganisms on all the implants that are in the body, "said Tim Holm Jakobsen, a researcher at the Costerton Biofilm Center at the University of Copenhagen. He is the first author of the new research article
Although the study finds microorganisms by a little more than two-thirds of implants, they are all likely the research group.
They could only study a small part of the implant. That's because it's hard to get out without getting in touch with the surroundings. Thus, the bacteria may have been located elsewhere on the implant.
Therefore, scientists believe that bacteria usually involve implants on the body, "says Tim Holm Jakobsen. tested a fraction of the implant. As a result, we barely found everyone, "said Jakobsen.
The human body is not sterile
The results are exciting, says Professor Emeritus Kilian Mogens.
– He This is a comprehensive study. "Mogens Kilian, professor emeritus at the Department of Biomedicine at Aarhus University, explains," He did not contribute to the research. " study, but he studies the human microbiome because it is the bacteria and fungi, for example, found in the oral cavity,
The idea of research was born
Thomas Bjarnsholt had the l & # 39; idea to examine implants in patients without symptoms after a discussion with scholarly legend Bill.Costerton, the Costerton Biofilm Center research center at the University of Copenhagen, is named after
Costerton discovered that clumps of bacteria, called biofilms, are the cause of the infection chronic ions in people with implants. Infections are harmful microorganisms that adhere to the implant and can not be eliminated with antibiotics.
The two researchers wondered if it was common for bacteria and other organisms to attach to implants in the body, even if the patients have no symptoms. He gave Thomas Bjarnsholt the idea of the study
– Although it has been known for a long time that there are microorganisms in the body, it has been assumed that the blood was sterile. However, it turned out to be wrong, Kilian said.
– This study shows that the body is not sterile. Probably the bacteria have crossed the blood and have been placed on the implant
The microorganisms can protect against infection
The new study says nothing about the possible effects of microorganisms on patients, but it can indeed be positive. lives in a dense symbiosis with bacteria and fungi. We can not live without them and they can not live without us. Bacterial scientists find implants around, bacteria that we know are harmless and can help prevent pathogenic bacteria, "said Kilian.
The result leads to more new questions, says Thomas Bjarnsholt.
– We Certainly, the role of bacteria and fungi plays when they are on the implant.Maybe they protect against harmful bacteria.Maybe it allows to have implants, says Bjarnsholt
– Perhaps we can prevent chronic infections by allowing certain bacterial species and fungi to grow on the implant before inserting it .It would be really amazing. [19659002] Reference:
TH Jakobsen et al .: "Implants induce a new niche for microbiomes" DOI: https://doi.org/10.1111/apm.12862
ller Science. dk. Translated by Lars N ygaard for research.no.
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