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(Newser)
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Fecal transplants, although experimental, have saved lives, reports the New York Times, citing the cases of some patients who were ravaged by "uncontrollable diarrhea" caused by C. difficile bacterial infection. But in a recent case, such a transplant was deadly. The FDA announced Thursday that a patient had recently died from a fecal transplant, in which healthy feces from a donor are treated in a laboratory and administered to a patient via an infusion or pills in order to restore the bacteria from the intestine. The FDA has stated that it is putting an end to the clinical trials of fecal transplantation until the researcher can prove to the FDA that she has measures to verify that the feces do not contain any faecal transplantation. deadly bacteria. This was not the case with the patient who died.
This patient, with a second patient, received stool from the same donor who had not been screened and developed infections. Once sick, the remaining stool samples from the donor showed that it contained multidrug-resistant microbes: E. coli, which produced extended-spectrum beta-lactamase. The FDA did not give details about the identity of the patients, nor about the treatment for which they were being treated, nor about the location of the transplant, although they claimed that their immune system was compromised and they were participating in a clinical trial. According to NBC News, fecal transplants are typically used to treat C. difficile. According to CDC statistics, 29,000 Americans are killed each year, according to CDC statistics. United States today notes that antibiotic-resistant infections kill 23,000 others. The FDA has pointed out that all standard treatments for C. difficile should be tried first. (Read more stories of fecal transplants.)
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