Peyton Elizabeth Lee to star in female-led Doogie Howser reboot from Disney +

Disney announced Thursday that Peyton Elizabeth Lee will don the white coat and stethoscope during the upcoming Disney + reboot of Doogie Howser, MD

The 16-year-old actress will take over the role played by Neil Patrick Harris in the original ABC series, which ran from 1989 to 1993.

It is the most prestigious role to date for Lee, who previously played the title role in the Disney Channel original series Andi Mack.

New Face: Peyton Elizabeth Lee, 16, to star in female-led reboot of Doogie Howser for Disney +, renamed Doogie Kameāloha, MD; seen in 2019 in Hollywood

The new half-house medical series has been transplanted to Hawaii and will be renamed Doogie Kameāloha, MD, to reflect the character’s background.

Later Thursday, Deadline reported that Episodes actress Kathleen Rose Perkins would also be joining the series in a lead role.

In the rebooted series, Lee will play 16-year-old Doctor Lahela “Doogie” Kameāloha.

The Métis teenager must balance her social life with the commitments of a high-pressure medical career.

Old School: Neil Patrick Harris played the main character in the original series, which ran from 1989 to 1993, as a 16-year-old doctor. Lee’s character was renamed Lahela “Doogie” Kameāloha; still advertising for Doogie Howser, MD

Main Part: Episode actress Kathleen Rose Perkins would also join the series as the Irish “spitting” mother of Lahela, who is also a doctor and supervisor at the hospital; seen in 2017

Perkins will play Lahela’s Irish mother, who is also a doctor and her supervisor at the hospital.

She also has a Hawaiian “Local Boy” father who finds it difficult to accept that his daughter is soon to be an adult.

Executive producer Kang, who previously worked with Perkins on ABC’s Fresh Off The Boat, will lead the rebooted series.

In the original series, created by the late Steven Bochco and David E. Kelley, Doogie’s father was a doctor, while he had a stay-at-home mom.

The new reboot will remain in the family, as Bochco’s widow Dayna Bochco and their son Jesse Bochco will produce the series with Kang, Jake Kasdan and Melvin Mar.

Good start: Lee was part of a historic cast during his three-season run on Disney’s Andi Mack. She played the main character, who learned at the start of the series that her older sister was actually her mother.

Making Progress: The series was the first on Disney Channel to feature a gay lead character; publicity still from Andi Mack

Lee was part of a historic cast during his three-season series in Disney’s comedy-drama Andi Mack.

She played the main character, who learned at the start of the show that her traveling older sister was actually her mother.

Andi Mack was the first Disney Channel series to feature a gay main character.

Joshua Rush played Andi’s friend Cyrus, who turned gay in the show’s second season after developing a crush on the same boy Andi was interested in.

Off-camera, Lee has a recurring voice role in Disney’s The Lion Guard, and she has previously appeared on the now-canceled ABC crime series Stumptown.

Booming career: Off-camera, Lee has a recurring voice role in Disney’s The Lion Guard, and she has previously appeared on the now-canceled ABC crime series Stumptown; seen with Skylar Astin in 2019