Pfizer and Moderna COVID-19 vaccines present no safety concerns in first month of deployment, CDC says



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No safety concerns were associated with the Pfizer and BioNTech or Moderna coronavirus vaccines during the first month of deployment, the Centers for Disease Control and Prevention (CDC) reported on Friday. No deaths have been attributed to the vaccines either, the health agency noted.

The report, which included data on the first vaccines given from December 11 to January 13, 2021, found that the most common symptoms associated with bites were headache, fatigue and dizziness. While 113 deaths were reported to the vaccine-related adverse event reporting system, none of the data suggested a relationship to the COVID-19 vaccine.

The agency noted “rare cases” of anaphylaxis in the Pfizer and Moderna vaccinees, but this was not outside the range of those seen with other vaccines.

“The occurrence of anaphylaxis following receipt of COVID-19 vaccines during the analysis period, 4.5 cases per million doses administered, is within the range reported after receipt of inactivated influenza vaccine (1.4 per million), pneumococcal polysaccharide vaccine (2.5 per million), and live attenuated herpes zoster vaccine (9.6 per million); there are effective treatments for anaphylaxis (6), ”the report states.

The agency also said that adverse reactions to the Pfizer vaccine were more frequently reported after receiving the second dose than the first, but information about the second dose of Moderna was not yet available due to dosing intervals. .

“The first postauthroziation safety profiles of the two COVID-19 vaccines currently in use indicated no evidence of unexpected serious adverse events,” the report said. “These data provide reassuring and useful information about what health care providers and vaccinees can expect after vaccination.

During approximately 30 days of monitoring, over 13.7 million doses have been administered. Across the United States, the deployment got off to a rocky start, with confusion over schedules, supply constraints and concerns about wasted doses.

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Supply continues to be a concern among states, with the United States currently receiving an average of 1.7 million doses administered per day, but people continue to see long wait times or canceled appointments. On Friday, the White House noted that winter storms had impacted the shipment of supplies entering each of the 50 states and that about 6 million doses were withheld. Andy Slavitt, White House COVID-19 adviser, said he expects the delayed supply to catch up in the coming days.

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