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Yomiuri ShimbunNew findings indicate mammoth resurrection is not a fantasy, said a research team of Kindai University members after cell nuclei were discovered from the remains of a 28,000-year-old woolly mammoth .
Once placed in mouse eggs, the nuclei grew into a state just before cell division, according to an article published Monday in the British journal Scientific Reports.
The team includes researchers from Japanese and Russian universities. He has been working for about 20 years on a project to use cloning to resuscitate mammoths, a long-extinct animal.
The cell nuclei used in the team's recent findings were extracted from the musculature and other tissues of Yuka, a woolly mammoth about 3.5 meters long, excavated almost intact in 2010 in permafrost in Siberia. . Once inserted into mouse eggs, it was observed that five of the 43 nuclei were growing at a point just before the nuclei split in two as a result of cell division.
The cell nuclei contain DNA, the so-called plan for life, and mouse eggs have been confirmed by experiments as having a restorative function for the DNA. It is possible that the mammoth's DNA, damaged because of its prolonged frost, has been repaired and its biological functions reinvigorated.
However, the development of predivision stopped before completion in all eggs.
"Yuka's cell nuclei have been more damaged than we thought and it would be difficult to resuscitate a mammoth in the state," said Kei Miyamoto, a member of the team, a professor of developmental biology at the University of Hawaii. Kindai University. "There is a chance, if we can get better preserved kernels."
Teruhiko Wakayama, professor of reproductive biology at the Advanced Biotechnology Center at Yamanashi University, said, "This is a first step in the search for the dream of resurrecting extinct animals. I hope that they will be able to determine to what extent the DNA has been repaired and what activity there was. "Speech
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