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As a result of clinical trials, a drug has been successful in reducing brain damage in patients with Alzheimer's disease. Thus, the progression of the disease has been slowed down.
According to the results published by the International Conference of the Alzheimer's Association in Chicago, the drug could be the first of its kind to manage changes in the brain as well as the symptoms of Alzheimer's disease. "Clinical trials show changes in wounds and cognition," said Dr. Reisa Sperling, director of the Center for Alzheimer's Research and Treatment at Brigham, who was not involved in the study [19659003] The total lunar eclipse 27 July. All you need to know about the longest eclipse of this century
The NY Times writes that apart from a few medications that slow the decline of memory for several months, there is no treatment effective against Alzheimer's disease, a disease that affects 44 million people. globally. It is estimated that these numbers will triple by 2050.
850 American, European and Japanese patients with early symptoms of cognitive decline participated in the trials. They have been diagnosed with early cognitive impairment or dementia, with deposits of amyloid proteins in the brain. The drug called BAN 2401 was created by a Japanese company in collaboration with Biogen, a Cambridge company.
In the recently presented results, patients who received five doses of treatment injected for two weeks reduced their amyloid levels and cognitive decline. Of the 161 patients in the highest dose group, 81% had significant signs of decreased amyloid. In the case of memory and planning tests, the group receiving the highest dose experienced a 30% lower rate than control group members.
Dr. Lynn Kramer, director of the Japanese pharmaceutical company EIsai, said that statistically the best results were observed in patients who had been treated for six months. However, in a company report in December 2017, it was reported that 12 months of testing did not show a significant decrease in the development of dementia. After 18 months of testing, the results became more positive, but not enough for the drug to be considered effective.
Although testing continues, it will take many years for the drug to be available worldwide.
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