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Researchers in North Carolina have found a potential treatment for kidney cancer. Genetic changes can lead to an abundance of blood vessels that help to "feed" the tumor. But the new discovery demonstrates the possibility of a new way to develop cancer
More than 90% of the most common types of kidney cancer are fueled by genetic changes that lead to the loss of the VHL gene suppressor. tumor. According to Science Daily, specialists have identified a new effect of genetic alterations favoring kidney cancer, according to descopera.ro.
The researchers suggest that the ZHX2 protein may be a new therapeutic target for the destruction of renal cell carcinoma. "If we lose VHL, it will accumulate a lot of ZHX2 proteins that will promote the appearance of signals that promote kidney cancer.The protein may be a therapeutic target used to treat kidney cancer." The next step to find out how we can destroy it therapeutically, "said Qing Zhang, a professor at the University of North Carolina.
Renal cell carcinomas occur in 70% of cases, experts say About 90% of these patients have genetic mutations or alterations that lead to loss of VHL gene function.When gene functions go away, cells accumulate signals that lead to the growth of blood vessels. " 39, one of the most important carcinoma suppressors, "said Zhang.
Researchers have created a new screening technique to discover the new molecule that for would help stop the effects of the disappearance of VHL. By removing ZHX2 from laboratory models, specialists have inhibited the growth of cancer cells and their spread.
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