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And the Food and Drug Administration announced its approval of emergency use of the vaccine for adults aged 18 and older, after its committee of external experts unanimously approved it on Friday.
In response to numerous questions, Maureen Ferrand, a virologist at the Rochester Institute of Technology, answered a number of questions related to the “Johnson & Johnson” vaccine, according to the “Economic Times” website:
How does the vaccine work?
The Johnson & Johnson vaccine is called what are called “viral vectors” because the team that developed the vaccination took an attenuated “adenovirus” virus with 52 different serotypes, and they replaced a small part of its instructions. genetic by the genes of the Corona virus, that is to say the protein “SARS-Cove”. -2 “.
Then, the cells read the genetic instructions necessary to make the “spike” protein, so that the immune system notices the “intruder” protein, and generates antibodies that protect the person in case they are exposed to the virus in the future.
Adenovirus vectors are completely safe and the most suitable for genetic modification, because the vector is a virus from which the reproductive gene has been removed and therefore does not pose a threat to the body in terms of infection.
How effective is it?
In global vaccine trials that included 44,000 people, the vaccine was found to be 66% effective in preventing moderate and severe infection with the coronavirus four weeks after vaccination and 100% in preventing hospitalization. and deaths from illness.
How is it different from other vaccines?
The Johnson & Johnson vaccine depends on adenovirus vectors, while the Moderna and Pfizer vaccines adopt messenger RNA technology, that is, using the genetic instructions of the coronavirus to tell a person’s cells to make an advanced protein, without using another virus. As a vector.
The vaccination of the vaccines “Moderna” and “Pfizer” is also done in two doses, while the vaccine “Johnson & Johnson” is administered in a single dose.
Johnson & Johnson vaccine can be shipped and stored in regular refrigerators, making it easier to distribute compared to Pfizer and Moderna vaccines, which must be kept at freezing point.
Should we prefer one vaccine to another?
Medical studies and research indicate the safety of all vaccines provided to prevent the emergence of the corona virus, so experts recommend that individuals obtain any vaccine available to them, due to the effectiveness of different types of. vaccination against Covid-19.
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