A unique case study of a girl with “mirror movement” and a rare disorder!



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If you are sitting at the piano, playing different notes with each hand is the first step in mastering an instrument. But what if both hands were determined to do the same?

Arguably this is the experience of people who suffer from a rare condition known as mirror movement, and doctors have now documented a single case as researchers in India have identified a case of this condition. extremely rare in a 13 year old girl several years ago and were also diagnosed with a chromosomal disorder. Turner syndrome.

Most young humans take a long time to become adept, but by the age of 10, the connection between the two hemispheres of our brain allows us to bend, prick and wave the fingers in each hand, regardless of one of the the other.

For about one in a million children, this development is incomplete, meaning that the actions of one hand are simultaneously resonated by the other.

The underlying cause of this “fake cat” movement is still largely a matter of guesswork, although there is reason to suspect that the major nerves in the brain are “crossed” as a result of the formation of bad synapses. between neurons.

And in nearly a third of cases, mutations in two genes seem to be responsible, hampering the development of the nervous system in such a way that instructions are mistakenly transmitted from either side of the brain to both sides of the body. And for the rest of the recorded cases, it is clear that there is still a lot to learn about the brain and its development.

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For example, people with cerebral palsy will show varying degrees of mirror movement. Parkinson’s disease is another condition that can accompany this form of synchronicity, especially if it affects one side of the brain more than the other.

It can also coincide with the behavior, the presence of ruptures or the lack of communication between the two halves – a bridge of neurons called the corpus callosum. A genetic link has been revealed in several of these cases.

Kallmann syndrome is a condition caused by a lack of certain hormones, which results in characteristics such as decreased smell and delayed puberty. And sometimes the movements are reversed.

Turner syndrome is also a condition that affects the body’s ability to coordinate hormonal responses.

Before this condition, no one had recorded a person with a chromosomal abnormality who also underwent reverse movements.

The syndrome is caused by the lack of a second X chromosome, leaving people with the disorder with only one X to do the job. The consequences can be anywhere in the body, ranging from heart defects to low height and failure of ovarian growth.

And in the particular case of this little subject, there was a slight physical strain, and an absence of secondary sexual characteristics. The echocardiogram revealed that there was a valve with two aortas instead of the usual three flaps, but otherwise everything looked healthy.

In addition to poor school activity, the patient’s speech and other neurological signs were as expected for a child his age. However, due to the task of counting to five on her left hand, her right hand couldn’t help but join it.

The MRI did not reveal any surprises, and without the resources to take a closer look at his brain physiology, medical staff at the Sri Ramachandra Institute of Higher Education and Research must have assumed it was ” just one of those things ”.

Because mirror movements are so rare, and Turner’s syndrome affects only 1 in 2,000 women, it’s difficult to determine if this is a coincidence or if there is some sort of connection that we might have. say more about the two conditions. Medical science is often about noting new findings like this and patiently waiting to see if future results add to the evidence.

https://www.youtube.com/watch?v=s1oktdkboKI

And for the girl, who is now 19, the endocrinologists wrote: “Looking at her age, she started taking gradually increasing doses of estrogen followed by progesterone treatment.”

This case study was published in the journal BMJ Case Reports.

Source: ScienceAlert



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