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Bowel cancer is a broad term for cancer cells that grow out of control in the large intestine (colon and rectum), if not caught early.
And because the symptoms of bowel cancer can be subtle and not necessarily make you sick, they usually go undetected until you develop.
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Scientists warn that the presence of a certain type of bacteria in the gut can increase the risk of developing bowel cancer by 2 to 15%.
Bowel cancer affects more than a quarter of a million people each year, and in industrialized countries the lifetime risk of developing the disease is around 5%.
When the disease is localized or contained, the cure rate can vary from 70% to 90%, but advanced bowel cancer has a high death rate and is consistently ranked as the top three causes of cancer death in the world.
A person’s gut is a densely populated microbial ecosystem, and if it contains certain bacteria, it can increase the risk of developing a fatal disease.
Studies indicate that infection with a common type of oral bacteria can contribute to bowel cancer.
The bacteria, nicknamed “Fusobacterium nucleatum,” can attach to colon cells and lead to a series of changes that can lead to bowel cancer, according to the team at the School of Dentistry at Case Western Reserve University.
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Scientists have found a way to prevent bacteria from attaching to cells in the colon. “This discovery creates the potential for new diagnostic tools and new treatments for the treatment and prevention of cancer,” lead researcher Yiping Han said in an academic press release.
Han, professor of periodontal disease, added that the results show the importance of good oral health. And in a study published in the U.S. National Library of Medicine, National Institutes of Health, additional research was conducted on microorganisms, microbes, and colon cancer.
The study indicated that the human colon is also an anatomical site with the greatest number of microbes. It is therefore natural to expect the role of microbes, in particular bacteria, in colorectal carcinogenesis.
The researchers said, “There is a long-standing curiosity about the role of bacteria in colon and rectal carcinogenesis, due to the high disease burden of colorectal cancer and the microbial burden of the colon.”
Diets high in saturated fat increase bile acid production, and several studies have identified the association between diets high in saturated fat and colorectal cancer.
Gut bacteria are important factors in bile acid metabolism and therefore may play a role in the biology linking bile acids to bowel cancer, the researchers say.
In another study published on the “Science Daily” site, colon cancer caused by bacteria and cell tension was analyzed.
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Professor Dirk Haller from the Department of Nutrition and Immunology at the Weihenstephan Science Center at TUM said: “Through our study, we originally wanted to investigate the role of bacteria in the gut in the development of enteritis. , but the surprising result for us was the discovery that the stressed bacteria in cells cause tumors (exclusively in the colon) and without involvement in inflammation. “
He added: “In some patients, ATF6 may act as a diagnostic marker of an increased risk of colon cancer, and it may indicate the start of treatment at an early stage.”
He continued, “Microbial treatment can be imagined, when more is known about the formation of bacterial flora. But what has become clear now is that chronic inflammation has no effect on the development of the bacterial flora. cancer in the colon. “
The American Cancer Society has said that diets with lots of vegetables, fruits, and whole grains are associated with a reduced risk of colon or rectal cancer.
The association’s website advises: “Cut back on red meat and processed meats, which have been linked to an increased risk of colon and rectal cancer. If you are not physically active, you may have a higher risk of developing colon or rectal cancer. Increasing your activity may help reduce the risk. “
Source: Express
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