Moderna develops twice as many antibodies as the Biontech vaccine | health | Essential information for better health | DW



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The American Moderna vaccine develops twice as many antibodies as a dose of the Pfizer-Biontech vaccine. This is the conclusion of a study published in the Journal of the American Medical Association, according to the German site “Focus”.

The study included a follow-up of 2,500 workers in Belgian hospitals, where it was found that the level of antibodies in individuals who were not infected with the coronavirus emerge before receiving two doses of Moderna vaccine. at an average of 2,881 antibody units per milliliter, compared to 1,108 units per milliliter in a similar group who got two doses of the Biontech-Pfizer vaccine.

Researchers overseeing the study thought the reason may have been that the Moderna vaccine contains a larger amount of the virus’s active ingredients, 100 micrograms, compared to 30 micrograms in the Pfizer-Biontech vaccine. It can also be caused, the researchers explained, by the time interval between the first and second dose of the vaccine, in which Moderna places a 4-week interval between the two doses, compared to three weeks between the two doses of Biontech. -Pfizer. .

As in previous studies, the study generally indicates that a strong antibody response provides good immune protection against the Corona virus. However, this is not the only determining factor. The human immune system is very complex and interacts on several levels. Therefore, T cells play an equally important role in preventing future infections.

“Antibodies alone don’t necessarily tell you how protective you really are,” German immunologist Carsten Wassel said in an interview with DW. “You can definitely have very low amounts of antibodies, which means you can get infections, but you can have a strong T-cell response, which keeps you from getting very sick,” Vazel continues.

However, these T cells were not examined in the Belgian study.

AM / AH



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