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Nicotine consumption by smokers trying to quit smoking will probably help them get rid of this habit, according to a recent study conducted by 50 people led by Queen Mary University in London, reported Wednesday. British Medical News website.
In the first study to determine nicotine doses based on smokers' choices to quit smoking, the results indicate that most smokers who use these drugs can easily tolerate doses 4 times higher than those usually recommended ..
"Smokers limit their nicotine consumption when they smoke, but when they try to quit, their nicotine levels are determined by the recommended treatment doses, and these levels may be very low in some people ", said author of the study, Dunga Brez-Lage, of Queen Mary University in London. Increases chances of their return to smoking.
She added that medical products containing nicotine may be inferior to the amount of nicotine absorbed by the smoker during smoking and may explain this failure of antismoking treatments, so it is necessary to modify the application,. "Our results reassure smokers that it is ok to use the doses of nicotine they find useful. "
Nicotine stick to get rid of tobacco
When nicotine replacement therapy was first evaluated in the 1970s, low doses were used because of concerns about toxicity and addiction. However, drugs to stop smoking contain less nicotine in their products
The new study, published in the journal "Education", examined 50 smokers in a tobacco clinic in Argentina, the first in the world to have tried a nicotine common approach before the start date, and recorded nicotine levels based on the patient's observations.
Participants started the day with 21 mg of nicotine four weeks before the start date and the dose was increased by 21 mg weekly, unless participants report adverse effects. The dose was increased by 4 adhesives per day, for a total of 84 mg / day. The dose was reduced by 21 mg, until it regained the standard dose (21 mg / day) after 4 weeks.
Quit smoking with nicotine
Participants were encouraged to continue smoking as desired during the pre-cessation period, and oral nicotine replacement therapies were suggested.
4 weeks of abstinence in 82% of participants, no significant increase in withdrawal symptoms; Cigarette smoking, smoking and smoking decreased significantly in the period before quitting. The intervention was classified as useful and easy to follow.
Prior to the start-up period, the number of cigarettes that he smoked each day had decreased significantly, from 20 cigarettes per day initially to 6 per day at takeoff.
The number of adverse events increased with the increase in the dose of nicotine. Most of these symptoms were nausea, common sensations, followed by vomiting, but most were moderate and well tolerated.
Two of the participants described their adverse effects as "severe", both at 63 mg.
Stop smoking
One participant reported feeling headache, nausea and fainting when he reduced the dose to 42 mg daily, leaving only 6% of patients.
"Smokers are able to determine the doses of nicotine that they find useful," said Peter Hagik of Queen Mary University in London. "There is no risk of overdose because nicotine contains an effective safety valve in the form of nausea.
Our findings also suggest that one of the reasons that e-cigarettes are more popular than other nicotine replacement treatments is that smokers can adjust nicotine doses according to their needs.
Nicotine treatment is thought to help weaken the conditional association between smoking and reward behavior, and to reduce the pleasure of smoking.
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