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Researchers have developed a new mechanism focusing on genetic changes
Newspapers have revealed that for the first time in the world, scientists have discovered a way to recover lost memories.
The researchers published a report on a new study on how researchers at the University of Buffalo, United States, have found a way to restore memories lost because of Alzheimer's disease.
The researchers have developed a new mechanism that may reflect memory loss in patients with Alzheimer's disease by focusing on the genetic changes caused by the effects of DNA sequences, called "epigenetic" .
"We have not only identified the genetics that contributes to memory loss, but we have also found a way to temporarily reverse it in an animal model," said Chen Yan, a professor at the University of Buffalo and lead author of the study.
The research was performed on mouse models carrying genetic mutations bearing Alzheimer's disease. The family has more than one individual with Alzheimer's disease and brain tissue from patients' brains suffering from Alzheimer's disease after their death.
"Alzheimer's disease occurs primarily when patients are unable to retain the information they have learned recently, and they further demonstrate the cognitive decline due to the loss of glutamate receptors, which are essential for learning and memory. in the short term, "Jan said.
The researchers found that the loss of glutamate receptors was the result of a genetic process called "repressive modification of the histone", very high in patients with Alzheimer's disease.
In this study, researchers were able to correct the cognitive impairment of patients with Alzheimer's disease by targeting lignin enzymes, which restore glutamate receptors, by injecting three times the patients with the disease. Alzheimer's compounds designed to inhibit the enzyme that controls the repressive adjustment of histones, as well as to restore cognitive functions and spatial memory. And working memory.
"Alzheimer's" .. Scientists find a way to recover lost memories
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2019-01-29
Newspapers have revealed that for the first time in the world, scientists have discovered a way to recover lost memories.
The researchers published a report on a new study on how researchers at the University of Buffalo, United States, have found a way to restore memories lost because of Alzheimer's disease.
The researchers have developed a new mechanism that may reflect memory loss in patients with Alzheimer's disease by focusing on the genetic changes caused by the effects of DNA sequences, called "epigenetic" .
"We have not only identified the genetics that contributes to memory loss, but we have also found a way to temporarily reverse it in an animal model," said Chen Yan, a professor at the University of Buffalo and lead author of the study.
The research was performed on mouse models carrying genetic mutations bearing Alzheimer's disease. The family has more than one individual with Alzheimer's disease and brain tissue from patients' brains suffering from Alzheimer's disease after their death.
"Alzheimer's disease occurs primarily when patients are unable to retain the information they have learned recently, and they further demonstrate the cognitive decline due to the loss of glutamate receptors, which are essential for learning and memory. in the short term, "Jan said.
The researchers found that the loss of glutamate receptors was the result of a genetic process called "repressive modification of the histone", very high in patients with Alzheimer's disease.
In this study, researchers were able to correct the cognitive impairment of patients with Alzheimer's disease by targeting lignin enzymes, which restore glutamate receptors, by injecting three times the patients with the disease. Alzheimer's compounds designed to inhibit the enzyme that controls the repressive adjustment of histones, as well as to restore cognitive functions and spatial memory. And working memory.
January 29, 2019 – 23 Jumada I 1440
The time now is 09:04 AM
Researchers have developed a new mechanism focusing on genetic changes
Newspapers have revealed that for the first time in the world, scientists have discovered a way to recover lost memories.
The researchers published a report on a new study on how researchers at the University of Buffalo, United States, have found a way to restore memories lost because of Alzheimer's disease.
The researchers have developed a new mechanism that may reflect memory loss in patients with Alzheimer's disease by focusing on the genetic changes caused by the effects of DNA sequences, called "epigenetic" .
"We have not only identified the genetics that contributes to memory loss, but we have also found a way to temporarily reverse it in an animal model," said Chen Yan, a professor at the University of Buffalo and lead author of the study.
The research was performed on mouse models carrying genetic mutations bearing Alzheimer's disease. The family has more than one individual with Alzheimer's disease and brain tissue from patients' brains suffering from Alzheimer's disease after their death.
"Alzheimer's disease occurs primarily when patients are unable to retain the information they have learned recently, and they further demonstrate the cognitive decline due to the loss of glutamate receptors, which are essential for learning and memory. in the short term, "Jan said.
The researchers found that the loss of glutamate receptors was the result of a genetic process called "repressive modification of the histone", very high in patients with Alzheimer's disease.
In this study, researchers were able to correct the cognitive impairment of patients with Alzheimer's disease by targeting lignin enzymes, which restore glutamate receptors, by injecting three times the patients with the disease. Alzheimer's compounds designed to inhibit the enzyme that controls the repressive adjustment of histones, as well as to restore cognitive functions and spatial memory. And working memory.
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