Study: Tobacco Treats Diabetes And Arthritis



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MENA


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Thursday, February 28, 2019 – 11:12 am
| Last update:
Thursday, February 28, 2019 – 11:12 am

Canadian researchers have stated that it is possible to help tobacco produce an anti-inflammatory protein, which could have a strong therapeutic potential for the treatment of diseases such as type 2 diabetes, stroke , dementia and arthritis, more effectively and at an affordable price for many.

The joint research team at the University of Western Ontario and the Lawson Institute for Health Research in Canada has confirmed the possibility of helping tobacco plants produce large amounts of a protein called IL-37, produced naturally in very small amounts in human kidneys.

"This protein is the primary regulator of inflammation in the body and preclinical models have been shown to be effective in the treatment of many inflammatory diseases and autoimmune immunity," said Tony Geffenaker, a professor at the University of California. Western University. IL-37, but not enough to get us out of an infection. "

The first experimental studies of this protein have been shown in animal models, but they have been limited because of their inability to produce them in large quantities and at a clinically reasonable price. They can be made in very small amounts with the help of E. coli, but at a very high cost.

"Plants make it possible to produce pharmaceuticals in a much more expensive way than current methods," said Shingo Ma, a researcher at the Lawson Institute for Health Research in Canada. "The tobacco plant is very productive and we can change it temporarily in order to start producing interesting proteins within two weeks."

The team is currently studying the effect of IL-37 protein on the prevention of organ damage during implantation: when an organ is removed for implantation and then transferred to the recipient, inflammation occurs when blood flow is restored in the organ.

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