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London – Palestine today
A new study on anesthetized mice revealed that hallucinogenic phenomena of dramatic sensory changes might be due to weaker signals in the visual cortex, rather than increased, as expected.
"One could expect visual hallucinations to occur through the nerve cells of the brain, which emit inconsistent signals, and we were surprised to find that they were due to a decrease in 39, visual cortex activity, "explains lead author Chris Neal, an associate professor and associate professor at the Institute of Neuroscience at the University of Oregon.
In the study, mice received a hallucinogenic drug called 4-iodo-2,5-dimethoxyphenylisopropylamine, which acts on 2A receptors of serotonin. Images were then displayed on the screen in front of mice, and the researchers monitored the activity of their brain by calcium imaging.
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The images revealed that even after taking the drug, the signals sent were very similar to those seen in the absence of the drug, which means that the information itself does not change because of the hallucinogenic substance. The study suggests that visual hallucinations may result from weaker signals in the visual cortex and alter the timing of their release by neurons.
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