Colchicine for gout protects against diabetes



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According to a US study, a drug widely used to treat gout can help prevent type 2 diabetes.

The study was conducted by researchers at the Kennedy-Schriver National Unice Institute for Child Health and Human Development in the United States and published in the journal Diabetes, Obesity and Metabolism.

The team conducted its study on the efficacy of colchicine, a drug used to treat gout and relieve joint pain and inflammation.

The researchers tested the effectiveness of the drug to deal with the complications of metabolic syndrome, a serious disease that plays a major role in cardiovascular disease, hepatic steatosis and type II diabetes.

If you have at least three health problems, you may experience at least three of the following problems: abdominal obesity, high blood pressure, high blood sugar, low "good" cholesterol, high triglycerides.

To achieve the results, the team followed 21 obese participants who received colchicine twice daily for three months, while 19 obese participants also received a placebo.

The researchers found that the colchicine group had an improvement in the insulin resistance test needed to maintain normal blood sugar levels compared to the placebo group.

The first group also recorded a decrease in the number of tests indicating an increase in the level of inflammation in the body due to obesity and plays a role in the development of type II diabetes compared to the second group.

Dr. Jack Yanowski, head of the research team, said that colchicine inhibits a protein compound called NLRP3 and causes inflammation that appears in obese people.

He added that the study had proven that this drug protected against the complications associated with the metabolic syndrome, which increased the risk of type II diabetes.

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