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Researchers at the University of Geneva have succeeded in producing insulin through cells other than those produced by the University of Geneva, with the aim of providing a definitive cure for diabetes, which which limits the suffering of patients due to the frequent use of insulin injections.
Insulin is produced from beta cells, which are pumped into the blood, but researchers in the Nature study reprogrammed the alpha and gamma cells in the pancreas to perform this function.
The researchers obtained alpha and gamma cells from infected donors, then reprogrammed and transplanted them into the mouse. Four weeks later, they observed the response of the infected mice. These cells injected insulin in the required proportions up to 6 months after their implantation.
According to the study, gamma and alpha cells are extracted from the patient's pancreas and then genetically engineered to produce the ability to produce insulin by adding insulin copy agents in beta cells.
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