[ad_1]
A quick and comprehensive test for all types of cancer
Was able to diagnose 90% of cases in a short time
Thursday – 28 months Spring of the first 1440 H – 06 December 2018 AD Number [
14618]
London: Osama Noman
Researchers at the University of Queensland, Australia, have discovered a "unique DNA signature" that can detect all cancers. They added that they had successfully developed a new technique that can quickly and easily monitor any type of cancer in a blood sample.
Scientists have developed a series of tiny gold nanoparticles that have successfully detected cancer from the DNA of cancer cells in the blood. The research team of the Institute of Bioengineering and Nanotechnology of the University published the results in the journal Nature Communication.
"Because cancer is very complex, a variable disease, it is difficult to find a common fingerprint for everyone, different from that of healthy cells in the body," said Dr. Abu Ali Ibn Sina, assistant professor of biochemistry at the university. University concerned by the study. Scientists have therefore focused on a method called free rotary DNA test.
Cancer cells resemble healthy cells in that they die and renew themselves. But the cancer cells explode in their cells and release their charge, which carries their DNA, so that this acid circulates in the blood.
"Scientists are running behind a DNA signal distinct from the cancer itself and not from the body's cells," commented Dr. Sarah Carraskoza, co-author of the study.
Scientists have studied nanoparticles (nano-1 billion units) in the genome of cancer cells and healthy cells, with the goal of verifying the formation of molecules in the "methyl groups" that flank the DNA . These groups are important for cellular functions because they act as signals that control gene activation or stop working at specific times.
While these methyl groups spread throughout the genome in healthy cells, the research team discovered that the genome of the cancer cells is very poor, with the exception of the concentrated ganglia of these methyl groups, present in specific regions.
The scientists said that the only sign of cancer was the presence of these groups in each type of breast cancer and in all other cancers, including prostate cancer, colon, rectum and lymphoma.
Scientists discovered that the concentrated methyl groups were disintegrated when placed in a solution, resulting in the bending of DNA nanotubes glued to a gold material in a short time.
Scientists have therefore designed gold nanoparticles that change color when there is a part of the DNA. They tested 200 blood samples from different cancers and healthy cells. The accuracy of the test was 90%.
Dr. Abu Sina said the test "aims to monitor the genetic DNA of tissues, or the free acid that circulates in the bloodstream," adding that this discovery will change all cancer diagnostic methods. The study revealed that reprogramming genes at the level of nanotubes in cancer could regulate the physical and chemical properties of DNA and could lead to new methods of rapid diagnosis of the disease.
He added that the study had revealed that reprogramming genes at the level of nanotubes in cancer could regulate the physical and chemical properties of DNA and would give rise to new diagnostic methods.
America
The health
[ad_2]
Source link
