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There is currently no definitive diagnostic test for Parkinson's disease, but this can change thanks to a woman who can inhale the disease before the onset of symptoms.
Although it sounds strange, Joey Melne can actually feel the disease. She noticed the distinctive smell of her husband 10 years before being diagnosed with Parkinson's disease. When she took part in a meeting with other people with the disease, she realized that the smell was related. Disease.
Since then, scientists have been working with Joy to try to determine if they could specifically sense the disease, which appears to be related to lipid secretions that help keep our skin hydrated and naturally smelled, which can be produced more often at home. patients with Parkinson's disease. Parkinson's disease.
While Parkinson's is known to increase the production of sebaceous glands, scientists wanted to know specific biomarkers derived from the odor that Joy could capture. They therefore used a complete chemical spectroscopy to extract individual compounds.
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"We designed experiments to mimic what Joey was doing," said Perdita Baran of the University of Manchester in the UK. "We used the mass spectrometer to do what Joey could do when he smelled in patients with Parkinson's disease."
The team conducted a survey of 64 volunteers, some with Parkinson's disease and others in good health, to test and analyze the air's ability to capture the "super smell".
Scientists found that people with this disease had more "hippuric acid", "octadecanal", "eicosane" and other essential indicators in the sebaceous glands.
The presence of these molecular compounds is associated with varying levels of neurotransmitters in people with Parkinson's disease, who help neurons connect and control our thoughts and movements.
"This could have a significant impact not only on early and exclusive diagnosis, but also on helping patients monitor the effect of treatment," says Dr. Paran.
Joey says she can feel other diseases, such as Alzheimer's and cancer, so she can do a lot to advance science, especially since she works with the same team to test his early diagnosis of tuberculosis.
Early diagnosis of Parkinson's disease, well before the onset of symptoms, can help find treatments that can prevent the spread and development of Parkinson's disease.
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