Alzheimer's disease can be the source of the mouth



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Alzheimer's disease can be the source of the mouth

Bacteria that cause bleeding gums are transported to the brain

Monday 22 Jumada I 1440 H – 28 January 2019 Publication number [
14671]

London: Middle East

Scientists have discovered for the first time that bacteria responsible for bleeding gums can be transmitted from the mouth to the brain. The researchers found that the bacteria responsible for gum disease in the brain of 51 out of 53 participants had Alzheimer's disease. The results suggest that those who brush their teeth properly can reduce the risk of dementia, according to the Daily Mail newspaper.
The study found that Porphyromonas gingivalis, the leading cause of gum disease, was only able to reach the mouse brain six weeks after infection. The damage in brain memory centers of these mice may explain earlier evidence that people with long-term gum disease are 70% more likely to develop dementia.
Scientists now believe that bacteria can cause Alzheimer's disease in humans after discovering the toxic enzymes produced by brain, cerebrospinal fluid and rodent games diagnosed with the disease.
The study conducted by the American company "Corexyme", which states that the bacterium "Porphyromonas gingivalis" plays a "central role" in the development of Alzheimer's disease.
"This study is an important achievement to understand how to stimulate Alzheimer's disease and a new treatment underway," said General Manager, Casey Lynch.
Gingivitis, which causes bad breath and bleeding gums, has been associated with chronic health problems, including heart disease.
It was thought that oral bacteria could enter the bloodstream, entering cells believed to protect the brain and spreading over the brain for several years. Scientists have now shown that Porphyromonas gingivalis can actually pass from the mouth to the brain in mice.
Once infected with gingivitis, these animals showed brain lesions in the hippocampus, the critical area of ​​brain memory.
The mice also showed an accumulation of beta-amyloid, one of the devastating proteins of the brain believed to accumulate causing dementia.
"We know that diseases such as Alzheimer's disease are complex and have many different causes, but strong genetic evidence suggests that factors other than bacterial infection are at the root of disease development. of Alzheimer's, "said Dr. David Reynolds, Scientific Director of Alzheimer's Research UK. Results as part of this ongoing research ".

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