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Researchers at the center conducted an analysis on around 3,689 adults who were admitted to hospitals with severe Covid-19 from March 11 to August 15, 2021, which is the period leading up to and includes the spread of the delta mutant..
12.9% were fully vaccinated with Moderna, 20.0 with Pfizer / Biontech and 3.1% with Johnson & Johnson.
During the period, the Moderna vaccine was 93% effective against hospitalization, Pfizer 88% and Johnson & Johnson 68.%.
The loss of efficacy against hospitalization of the Pfizer vaccine was clear: it went from 91% at 14 to 120 days after vaccination, to 77% after more than 120 days after vaccination..
In contrast, Moderna went from 93% to 92% compared to the two periods.
The study also included a separate analysis of the levels of different types of vaccine-induced antibodies collected from 100 volunteers..
Moderna vaccine has also been shown to produce higher antibody levels than Pfizer and Johnson & Johnson vaccines..
There is a buildup of research indicating the superiority of the Moderna vaccine over the Pfizer vaccine, including studies by the Centers for Disease Control and Prevention published last week..
The reasons are still unclear, but it may be because the dose levels are higher – 100 mcg versus 30.
It may also be related to the interval between the two doses, as Pfizer is assigned a difference of three weeks compared to four weeks for Moderna..
And the United States Food and Drug Administration is hosting a meeting of leading independent experts to discuss the issue of giving third doses of Pfizer to everyone, not just people with low immunity..
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