Changing the functions of pancreatic cells to treat diabetes



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In a test conducted by a team of 4 Western universities on mice

A scientific team has been able to modify the initial function of pancreatic cells by achieving a breakthrough that could open up great prospects for the treatment of diabetes and possibly other diseases.

The cells can develop into cells of the same class and do the same work assigned to them, but researchers from the universities of Bergen, Norway, Geneva Switzerland, Harvard, the United States, Leiden Dutch and the Center American stem cells from Oregon have managed to alter the function of the cells. Scientists have discovered that body cells are able to switch to a different type of cell than expected.

"The team, by influencing the cells producing glucagon in the pancreas, has managed to push insulin secretion in place of glucagon," said Professor Helg Rieder, head of the stem cell group at Department of Clinical Sciences of the University of Bergen.

The scientific team monitored how mice were positive for diabetes after implantation in the body, how human cells functioned, and how the disease was transmitted to mice after removal of these cells.

In addition to pushing glucagon-producing cells to produce insulin, the study showed that new cells were resistant to the immune system, which normally attacks insulin-secreting cells in diabetics.

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