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Among the many variants of the Corona virus spreading around the world, news reports in India indicated that cases of infection with the Eta mutant were discovered in Mangaluru, Karnataka, India, according to what was published by the site. Web Boldsky, who is interested in health. business.
And it was confirmed that an Indian citizen was infected with the new variant on August 5, 4 months after returning from the trip, and Indian health sources said the case was not the first for the ETA variant in India or Karnataka. Earlier in April 2020, two people were confirmed to be infected with the Eta variant, and then it reappeared in July 2021, as a case of this strain was confirmed to Mizoram by the National Institute of Biomedical Genomics (NIBMG), after genome sequencing of 75 samples from the Indian state.
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Interesting eta variant
According to the US Centers for Disease Control and Prevention (CDC), the eta variant has the code B.1.525 and was first discovered in December 2020 in the UK and Nigeria.
The variant contains spike protein mutations and is classified as an “interesting” variant.
Reduce the effectiveness of treatment
It is known that the designation of the “variant of interest” of the SARS-CoV-2 virus contains specific genetic markers which can increase the binding capacity of high COVID-19 proteins to host cells, as well as reduce neutralizing antibodies, causing problems in diagnosis and reducing the effectiveness of treatment.
For example, the neutralizing antibody is produced naturally after infection or immunity induced by the vaccine. However, research results initially suggest that the eta variant may reduce the response of neutralizing antibodies, and thus potentially cause increased transmission or severity of the disease.
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Find out more
The eta variant can also cause a possible decrease in the neutralizing antibody response, which is acquired by monoclonal antibody therapies or convalescent and post-vaccination sera.
The eta variant contains mutations such as A67V, Q677H, and F888L, which are not found in any other variant of the novel coronavirus. But a study by a team of scientists from Italy, the United States and Belgium, updated on July 17, 2021, indicates that the Lota variant, first discovered in New York, also contains the same major mutations. eta.
How dangerous is ETA
The eta variant contains protein mutations similar to the alpha, beta, delta and gamma variants, which fall under the classification of a “variable of concern”, meaning an increase in the prevalence and severity of infection depending on the need for hospitalization and number of deaths, but the effect of the eta variant is small with regard to anti-neutralizing bodies.
The eta variant contains certain types of new mutations, the characteristics of which are still under investigation and study. Therefore, it is still not clear whether the eta variant can be classified as “alarming and fatal”, compared to other types of corona variants.
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