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Scientists at the University of Utah have discovered a way to treat autoimmune diseases, including type I diabetes. Researchers confirmed to the journal Nature Biomedical Engineering that they had put to the point an immunotoxin that destroys cells containing a deformed PD-1 protein, a control point that inhibits the activity of T cells and helps them to self-destruct. Transformations in the coding of the "PD-1" gene help to develop the reaction of tissues and organs of the body, causing various diseases. At the same time, "PD-1" is inhibited using grid inhibitors as an effective way to boost immunity against cancerous tumors.
An immunosuppressive test in mice with type I diabetes showed a slow progression of the disease for 10 weeks. People with autoimmune disease (MS) have decreased symptoms of paralysis. The use of this toxin reduced the number of cells containing the active PD-1 protein and the number of T cells in the inflamed organs.
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