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Washington –
In the largest study ever conducted on the genetic basis of Alzheimer's disease, US scientists have identified five new genetic mutations that make people more vulnerable to Alzheimer's disease.
The researchers analyzed the DNA of over 94,000 people, classified according to four genetic groups as part of the global genome project.
"The ability to combine data from many research groups has allowed us to discover new links to the causes of Alzheimer's disease," said Brian Kunkel, professor at the Johnby Hosman Institute of the Human Genome from the University of Miami to Miami. Adding that the time has come to study Alzheimer's disease is the most common cause of dementia in the elderly.
"We understand better how to read the instructions on Alzheimer's disease as a first step in clinical care," he said.
The researchers pointed out that learning more about how the five genetic variables affect the risk of Alzheimer's disease can improve knowledge about the onset of the disease and is a potential new target for therapeutic strategies.
The researchers also discovered that certain genetic variants associated with a protein called "Tao" could affect the development of Alzheimer's disease at an earlier stage than expected.
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