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"It's important to take into account the specific risk factors for women because they could eventually lead us to potential points of intervention," said Dr. Paula Jones, lead author of the study, researcher at Kaiser Permente.
During this study, the team examined more than 6,000 participants who underwent a medical examination and completed questionnaires on the first menstrual cycle, whether they were menopausal or had a hysterectomy.
The results showed that women who started the first menstrual cycle at age 16 or older were at least 23% more likely to die of dementia than women who started menstruating at age 13 or younger.
The team also found that women who were menopausal before the age of 47 were 19% more likely to develop dementia than women aged 47.
When the research team looked at the total number of years of maternity, from the first menstrual cycle to menopause, women younger than 34 years old were at an increased risk of dementia by 20%.
In addition, women who had a hysterectomy were 8% more likely to die of dementia than others.
Although members of the research team are still unable to understand the link between shorter reproductive years and an increased risk of dementia, they believe that hormonal levels may play a role.
Previous research has shown that estrogen has anti-inflammatory properties, which may increase the risk of dementia.
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