From a well-known animal .. a very strange technique to slow down aging

In new science, Irish researchers have found, thanks to a recent study, that fecal transplants from young mice to older mice help prevent cognitive decline, and they now hope to inspire new treatments in humans, according to the British “Daily Mail” published.

In detail, the study indicated that the microorganisms that live inside the human body affect health and vary with age, noting that the good bacteria can have beneficial effects on the immune system.

In research at University College Cork in Ireland, they took microorganisms from the stools of younger mice and put them in older mice, then tracked changes in the brain over time.

A more appetizing alternative

The results also indicated that the transplant technology produced specific changes associated with aging in older mice, indicating that future therapies that alter the balance of gut bacteria could help treat the cognitive decline associated with aging in the body. man in the future.

signs of aging

When it comes to rebuilding the balance of bacteria in humans, the researchers said, a dietary alternative to fecal culture may offer a more palatable solution.

Harnessing the microbiome

As the human body ages, beneficial bacteria gradually replace beneficial bacteria that cause chronic inflammation, metabolic dysfunction, and disease.

Irish researchers pointed out that microorganisms in the gut are autoimmunity, but they can also affect brain aging and increase the risk of neurodegenerative diseases.

John Cryan, Marcus Boehme and their colleagues transplanted fecal microbes from young mice aged 3 to 4 months into older mice aged 19 to 20 months and with cognitive function.

Billions of microorganisms

It should be noted that scientists have shown that 100,000 billion amazing microorganisms live in the human gut, whether beneficial or harmful, and the immune system is affected by the balance between the two types.

The Irish team showed that introducing certain types of gut microbes to older laboratory rodents from younger donors helped them think and remember.

The changes associated with aging were also reflected in the immune system, which allowed older mice to learn to run in mazes. .

Subsequent analyzes also showed that the brains of older mice were regenerated, containing metabolites and gene regulation patterns similar to those of adolescents.

In addition, the number of people with dementia worldwide is expected to triple to around 150 million by 2050 due to the aging of the world’s population.

Prof Cryan noted that microbes are moving back in time in aging mice and opening the door for new research into microbial interventions in humans, adding that a lot of work is needed first to translate the results into the future. ‘clinical use in humans.

Previous research has shown that a daily dose of probiotics over just 12 weeks can lead to significant improvement in elderly patients.