"Genome Guard" promotes the development of cancerous tumors once they are formed

NEW YORK (Reuters Health) – According to a recent study, a protein called p53, known as the "guard of the genome" for its reputation as a cancer repressor and cancer prevention, does not always protect the body against cancer.

According to the study published Jan. 31 in the journal Cancer Cell, the research team at the University of California, United States, has confirmed that protein blocks tumors by reducing oxidative phosphorylation which produces the toxins of the genome, Do it.

The research team came to this conclusion about "Genome Guard" after four years of research based on a combination of data from cell samples and models of rats and human patients, according to a report published by the University of California at the time of publication.

However, once this happens, it disrupts the natural function of the mitochondria, "the energy plants of the cell". The passage of oxidation phosphorylation, efficient energy production process in cells, to glycolysis, an alternative pathway. The energy helps to promote cancer metabolism.

Although there are treatments designed to improve the function of this protein in cancer patients, the research warns that it could unintentionally cause an adverse reaction, said Dr. Yang Xu, lead investigator of the drug. study in special remarks to "Al Ain News".

He added that the results of this research would play a role in the development of cancer treatment, that it is to activate the activity of this protein or the to discourage.