High levels of "testosterone" in women expose them to blindness

NEW YORK (Reuters Health) – A new study suggests that high levels of testosterone in women can cause brain disorders that can lead to blindness.

The study, conducted by the University of Birmingham in Great Britain, showed that excess testosterone leads to intracranial hypertension (IIH) for unknown reasons (high pressure in the brain) leading to blindness and to Daily long-term headaches in women.

The results also showed that women with IIH cranial hypertension had elevated testosterone levels compared with those with obesity and polycystic ovary syndrome. Hormones were also found to increase in the cerebral fluid of women with high blood pressure in skull B IIH.

Alex Sinclair, a researcher at the University of Birmingham, said the results were a big step forward. For the first time, we have discovered a unique pattern of regulation of intracranial hypertension (IIH) without androgens and could be a driver of abnormal brain pressure in people with this condition. "

"Given this, this is the first evidence that intracranial hypertension could be a manifestation of excess testosterone in women," Sinclair said.

For the current study, published in the journal JC Insight, the team examined testosterone levels in blood and urine, as well as brain fluid known as cerebrospinal fluid (CSF), at 55 women aged 18 to 45 infected. In cases of high blood pressure in the IIH skull. Then compare the results with the levels observed in obese women of the same body mass index and age, as well as in a group of women with polycystic ovary syndrome. .

It is known that PCOS is associated with an increase in the number of specific types of androgens, which can cause excessive hair and irregular menstruation.