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An American research team at the Salik Institute has developed a genetic mutation that impedes the mechanism of communication between the brain and muscles, which could be useful in the future in the treatment of cases with mobility problems, due to from one flaw of this mechanism, according to the eye to the newspaper.
According to the study published in the last issue of Neuron, good communication between neurons of the brain and muscles depends on the presence of guides acting to connect the signal of the brain to the muscles, like the work of the Himalayan alpinist guides. that guide those who wish to reach its peak.
The nervous system has 100,000 billion connections governed by 20,000 genes, of which about 10 are known for their guide. The most important communication is brain-muscle communication: the brain controls hundreds of different muscles to allow precise movements.
"When studying a sample of experimental mice, the research team was able to identify a genetic mutation at the origin of poor communication," said Dario Bonanoma, lead author of the study.
The research team identified the responsibility for the "p190" gene in communication and attributed the occurrence of an unwanted mutation of this gene to a lack of communication.
The next step of the research team will be to examine the control mechanism for this mutation and to determine the factors that influence the timing of its activity.
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