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Posted on the siteMedical News Today"The American report in which he spoke of a new treatment able to mitigate the toxic effects of chemotherapy for cancer and the undesirable side effects of certain chemical drugs.
The site, in this report, translates as "Arab"The researchers were able to develop" medical sponges "to absorb toxic chemotherapy when they" leak "from a member in treatment.
This innovative device can help reduce the harmful side effects of cancer treatments.
A team of researchers from various scientific institutions in the United States, including the University of California at Berkeley and the University of California at San Francisco, has developed a small sponge-like device to absorb chemotherapy drugs once arrived at the place to be treated.
The goal of the drug is to reduce the toxic side effects of chemotherapy, which destroys cancer cells but attacks and weakens healthy tissue. The outer shell of this absorbent polymer absorbs toxic substances after it passes through the target organ.
The researchers tested this new device as an adjunct chemotherapy treatment for liver cancer because the drugs are delivered to the liver through the bloodstream, increasing the side effects of chemotherapy.
The researchers announced their experiments and their findings in an article published yesterday in the Journal of the American Chemical Society.
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"For surgeons to insert this new device into the body, they will insert a thread into the bloodstream and place the sponge as a stent, leaving it in the course of chemotherapy," said Professor Nietash Basler of the University of California at Berkeley. It's been a few hours. "
The researchers tested the pig's sucking device after injecting it with a chemical drug to treat liver cancer and found that it could absorb 64% of the drug.
"We are developing this device to fight liver cancer, which is a major threat to public health, we are recording tens of thousands of new cases every year, and we are already treating liver cancer with intra-arterial chemotherapy." said Professor Steven Hates, co-author of the study.
"This device can be used to treat any tumor or limb disease, especially if the target has to absorb the drug from the vein before it moves to the rest of the body and that 39 it does not cause any undesirable effects. "
In the future, researchers plan to use this technique to treat kidney and brain tumors.
The site said Dr. Hitz had already used a safer way to deliver chemotherapy drugs to a specific place, instead of injecting them into the blood, inserting them directly into the catheter tube until the site of the tumor.
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This method will help to reduce the risk of access to and affect drugs.
But Hits reported that more than half of the injected dose was still leaking from the target organ and reaching other parts of the body.
The innovative absorption device, which contains an ionic polymer, is able to limit the spread of effective dicorubicin.
The research team explained that this device is actually inspired by industrial oil refining operations. Although this device has proven effective in healthy pigs, researchers have emphasized the need to check its effectiveness in clinical trials conducted with participants already infected with cancer.
For his part, Professor Hitz said that the next step would be preliminary tests of the effectiveness of this device in people with cancer, instead of continuing testing on small pigs whose liver would be good. health, as well as obtaining conditional approval from the US Food and Drug Administration.
The researchers believe that this innovative device will be promising in the treatment of cancer and that it will be more effective than the means to fight against the side effects of other chemotherapy treatments still under study.
"There are many opportunities to develop less invasive devices for the human body and to reduce the effects of the drug, and we think this idea will be applicable in general," said Professor Hitz.
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