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French and Spanish scientists analyzed published scientific articles on the effect of coronavirus on the central nervous system, and it became clear to them that delirium accompanied by high fever can be considered a symptom of “Covid-19 “.
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The Journal of Clinical Immunology and Immunotherapy reports that the majority of studies on the coronavirus focus on its impact on the lungs, heart, and kidneys. However, there is plenty of evidence that the virus affects the central nervous system, causing headaches and changes in cognitive function.
Scientists at the Open University of Catalonia in Spain and the University of Bordeaux in France came to the conclusion that delirium is one of these changes, along with the loss of smell and taste. It can therefore be considered as an early sign of infection with the coronavirus.
Delirium is a psychological disorder accompanied by confusion and inattention. It is often noticed when the temperature rises following infection with “Covid-19”, especially in the elderly, before the onset of cough and shortness of breath.
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Researcher Javier Correa, from the Open University of Catalonia, describes delirium as “a state of confusion in which a person feels disconnected from reality like in a dream”. We must therefore be vigilant in a pandemic period, because this case may indicate a coronavirus infection.
The basic hypotheses explaining the effect of SARS-CoV-2 indicate three possible causes: hypoxia or insufficient oxygen supply to neurons; Inflammation of brain tissue due to a cytokine storm; The virus enters the blood-brain barrier. Any of these three factors can trigger delirium.
The researchers point out that during the autopsy of patients who died from “Covid-19”, evidence is often found indicating brain damage related to hypoxia. According to them, hypoxia is probably the cause of delirium, cognitive impairment, behavioral disorders, inflammation of nervous tissue and brain damage in areas responsible for cognitive function and behavior, such as the hippocampus.
Source: Novosti
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