New Study Reveals … Alzheimer's Disease Caused by Mouth

In recent years, a great deal of scientific research on Alzheimer's has led to the hypothesis that Alzheimer's was not a disease, but an infection.

What prompted scientists to look for the origin and causes of this inflammation, and to the unexpected surprise, they found that inflammation of the mouth.

According to a scientific article by microbiologist Gian Botimba of the University of Louisville, this infection, which affects the gums, is the result of a disease known as porfiromonas jingivalis, a chronic gingivitis disease that infects often patients with Alzheimer's disease.

This is not the first time that chronic gingivitis is associated with Alzheimer's disease, Botimba said.

A scientific team performed laboratory experiments on mice, after transmission of oral disease (chronic gingivitis), to discover that inflammation led to the spread of bacteria in pathogenic parts of the brain, which led to Increased production of a substance called Scientists (amyloid beta), a sticky protein still present. Linked to Alzheimer's.

The Cortezim Pharma Complex's scientific team said they have not claimed the discovery of the main cause of Alzheimer's disease, but what has been accomplished so far is a breakthrough and a guide strong on the beginning of the disease, associated with oral diseases and gingival.

"Now, for the first time, we have strong evidence linking cells infected with chronic gingivitis and Alzheimer's disease," according to the team.

The researchers also discovered through the study of toxic enzymes called genespans, which are enzymes produced by bacteria in the brains of patients with Alzheimer's disease.

It is striking to note that the same toxic enzymes have been discovered by the brains of deceased people who have never been diagnosed with Alzheimer's disease.

According to researchers, this is important because the relationship between chronic gingivitis disease and Alzheimer's disease was not known in advance.

This raises the question of whether chronic gingivitis is the cause of Alzheimer's disease or whether dementia (a condition that usually affects the elderly and often leads to Alzheimer's disease) is what drives people not to take care of their mouth, and then to the occurrence of chronic gum disease, which causes Alzheimer later.

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"Drugs that target bacteria that are toxic to bacteria have proven useful until now for mice, but in the absence of new treatments for dementia for more than 15 years, it's important to test as much as possible, "said David Reynolds, chief research scientist responsible for research. Diseases such as Alzheimer's disease "

The researchers are optimistic about the future and what will be revealed in future research and studies on the disease.

"We will have to see the results of this experiment that are still going on before we know more about their healing potential for Alzheimer's disease."

Alzheimer's disease is one of the most prevalent diseases in the elderly and despite advances in scientific research, no treatment has been found to contribute to its elimination.

The American Alzheimer's Society estimates at nearly four million the number of people infected in the United States and about 14 million by 2050, in case a drug would not help. eliminate or reduce the incidence.