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According to a US study, a drug widely used for the treatment of gout can help prevent type 2 diabetes. Researchers at the Kennedy-Schriver National Institute of Unicef in the United States have published their findings Tuesday in the journal Diabetes, Obesity. and metabolism).
The team conducted its study on the efficacy of colchicine, a drug used to treat gout and relieve joint pain and inflammation.
The researchers tested the effectiveness of the drug to deal with the complications of the metabolic syndrome, a serious condition associated with cognitive impairment and dementia, as well as a major risk factor for cardiovascular disease, hepatic steatosis and type II diabetes.
A metabolic syndrome is diagnosed in the person with at least three of the following conditions: abdominal obesity, high blood pressure, high blood sugar, low "good" cholesterol, high triglyceride levels.
To achieve the results of the study, the team followed 21 obese participants who received colchicine twice daily for 3 months, while 19 obese participants also received a placebo. The researchers found that the group receiving colchicine had an improvement in the insulin resistance test, which estimated the amount of insulin needed to maintain a normal blood sugar level compared to the placebo group.
The first group also recorded a reduction of the interactive protein blood test and other tests indicating an increase in the level of inflammation in the body due to obesity and playing a role in the development of type II diabetes compared with in the second group.
The drug "colchicine" inhibits a protein called complex (NLRP3) and causes inflammation that appears in obese people.
"The study has proven that this drug prevents the complications associated with metabolic syndrome, which increases the risk of type 2 diabetes." According to the World Health Organization, type 2 diabetes is due to overweight and physical inactivity. Over time, high blood sugar can increase the risk of heart disease, blindness, neurology and insufficiency kidney.
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