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Viagra was manufactured by a group of pharmaceutical chemists working for Pfizer in England. In detail, researchers studied the use of this drug to treat high blood pressure and angina pectoris, and discovered its effectiveness in treating erectile dysfunction by chance.
The researchers were studying a drug to treat cardiovascular problems, supposed to dilate the blood vessels of the heart by blocking a protein called PDE-5 in animal tests.
In contrast, human trials have shown that the drug had little effect on angina pectoris.
The nurses who supervised the men involved in the study observed this strange story – which will become good news -. John Lamatina, who was responsible for Pfizer's research and development during the research, said many of them went to bed and were embarrassed because they felt right .
Dilated blood vessels have been found not in the heart but in the penis, and because vasodilation is an essential part of the process leading to erection. Pfizer then decided to market the drug to treat the problem.
The patent was registered in 1996 and was approved on March 27, 1998 by the US Food and Drug Administration for the treatment of erectile dysfunction. This is the first oral treatment for erectile dysfunction in the United States.
Viagra has become one of the biggest successes of the pharmaceutical industry: its annual sales in 2008 reached $ 1.934 billion in 2008 and, since 2012, the United States, Mexico and Canada spend about 1.4 billion dollars a year.
These figures are expected to decrease in the coming years, when the patent expires in 2020.
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